AM457 is a high-precision integrated amplifier which has been developed to condition signals from small differential input voltages within a range of a few millivolts (±5 to ±100mV FS). The chief component of the IC is a highly accurate, low-noise amplifier circuit (AMP). An additional integrated operational amplifier (OP) can be used to supply a sensing element with current or record temperature for sensor bridges powered by voltage, for example. The entire system (sensing element plus amplifier) is monitored by the integrated diagnostic unit which logs any sensing element errors or defects, system undervoltage, AMP overloads and excessive temperature. The various function groups are not mutually dependent on one another; the AMP can be operated independently of the OP, for example. The functionality of both component groups (AMP and OP) is autonomous with regard to the diagnostic unit. AM457 is a combination of high-impedance precision amplifier, additional OP and extensive diagnostic unit, enabling a self-monitoring sensor system to be assembled using very few components.