Abstract: The traditional data fusion algorithms based on synchronous data can’t get the holistic ’Best’ in the computation and estimation accuracy. And the existing asynchronous fusion algorithms have been mostly several questions, for instance time delay, the large computation and so forth. According to the existing questions of traditional algorithms, we take up with the design of the new fusion algorithm. Combing Multi-scale data fusion theory with process monitoring, we present a new process monitoring method based on(Multi-scale)data fusion, and finally present a application example. Key words:Data Fusion; Multi-scale; Fault Monitoring