This document outlines the basic steps and functions that are required to ensure the proper operation of the GC5325 System Evaluation Kit (SEK) system. The GC5325 is a fully integrated crest-factor reduction (CFR), digital predistortion (DPD) device capable of linearizing a typical base-station power amplifier (PA). This guide can help users to quickly evaluate the performance of various PAs with varying system parameters, such as CFR levels and PA input/output power levels before and after the DPD. The GC5325 EVM has two GC5325 devices configured to provide two separate transmit paths and uses one ADC for feedback that is shared by both GC5325 parts.