Contents 1 Introduction....2 2 Factors Affecting ADC Gain: When is Gain Calibration Necessary?.....3 2.1 Input Circuitry..3 2.2 PGA Setting.....3 2.3 Decimation Ratio.....4 2.4 Reference Voltage...4 2.5 What Doesn’t Affect the ADC Gain?.5 2.6 When should Gain Calibration be Performed?5 3 Self-Gain Calibration Command6 4 System Gain Calibration Command.7 5 Software Gain Calibration...8 6 Adjusting ADC Gain......9 7 Extending the ADC Input Range.....10 8 Recommendations.....11 References.....12 Figures Figure 1. ADC Gain Calibration after Self-Gain Calibration versus PGA Gain.3 Figure 2. ADC Normalized Gain Temperature Coefficient versus PGA Gain...5