As to the strict requirement of four channel time-interleaved sampling for clock,a new method that uses clock buffer AD9516 to provide four sampling clocks of 110MHz which differ by 90°in phase for four time-interleaved analog-to-digital converter is introduced in this paper.The characteristics of AD9516 and the circuit diagram are presented in detail. Making use of FPGA to simulate SPI protocol,the communication between AD9516 and DSP is realized by using the FPGA as bridge chip.