1 Introduction .... 1 2 Nature of the ECG Signal and System Design Implications ... 2 3 System Approaches ..... 3 4 ECG AFE with Low-Resolution (≤ 16-bit) ADCs ...... 4 5 Simplified Low-Cost ECG AFE with 24-bit Delta-Sigma ADCs 5 6 Sequential Sampling Measurements with the ADS1258 ....... 7 7 Simultaneous Sampling Measurements with the ADS1278 .... 9 8 References ... 10 List of Figures 1 ECG Signal Characteristics........ 2 2 System Approaches Based on ADC Resolution ...... 3 3 Typical SAR-Based ECG Signal Chain (Sequential Sampling) 4 4 ΔΣ-Based, Low-Cost ECG Signal Chain (Sequential Sampling) ......... 5 5 ΔΣ-Based, Low-Cost ECG Signal Chain (Simultaneous Sampling)...... 6 6 Test Setup Using the ADS1258... 7 7 Measured Time Domain Data ..... 8 8 Test Setup Using the ADS1278... 9 9 ADS1278 with Simulated 2-mV Cardiac Test Input. 10